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Neuroimmunology of
Host-Microbe Interaction

Research

Research

We use Drosophila to study the intricate interactions between microbes, the brain, and the immune system.

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  1. How does the brain sense the microbes?

  2. How does the brain inform the immune system about the infection?

  3. How is glia involved in it?

People

People

We are recruiting at all levels!

Interested in joining? Email to: wxu21@central.uh.edu

Features
News
News

Lab News

09/01/2024: The lab is officially open! Let’s begin exploring the exciting world of fly neuroimmunology!

05/26/2024: Lab logo announced!

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05/24/2024: Xu lab will open on September 1st in the Department of Biology and Biochemistry at the University of Houston!

publications

Selected Publications

  1. Xu, W., Rustenhoven, J., Nelson, C. A., Dykstra, T., Ferreiro, A., Papadopoulos, Z., Burnham, C.D., Dantas, G., Fremont, D. H., Kipnis, J. (2023). A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan. Neuron 111(20): 3244-3254.e3248. Featured by Science Signaling, 16(809): eadl5530.

  2. Xu, W., Bao, P., Jiang, X., Wang, H., Qin, M., Wang, R., Wang, T., Yang, Y., Lorenzini, I., Liao, L., Sattler, R., Xu, J. (2019). Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity. Brain 142, 1349-1364.

  3. Xu, W., and Xu, J. (2018). C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in Drosophila Glutamatergic Neurons. J Neurosci 38, 7741-7752.

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